尿道综合征症状呈多样性，尿频、尿急、排尿困难是其主要症状，与急性膀胱炎极为相似。下面从尿急及排尿困难两个方面，介绍一下尿道综合征的初期表现。
1.尿急
尿急是指不能自控排尿或排尿有急迫感，尿意一来，即需排尿，不可稍有懈怠;或排尿之后，又有尿意，急需排尿，不及时排尿，则会尿湿内裤。主要由于尿道、膀胱、前列腺因炎症或异物刺激所致，常伴有尿痛。
2.排尿困难
是指排尿时须增加腹压才能排出，病情严重时膀胱内有尿而不能排出称尿潴留。女性排尿困难可分为机械性和功能性两种，从膀胱、尿道任何部位的病变影响尿液排出而引起的排尿困难，均属机械性。泌尿管道通畅但膀胱肌肉无力，以及膀胱逼尿肌和尿道括约肌在排尿过程中不协调引起的排尿困难，都属功能性。神经性膀胱功能障碍常伴便秘，肛门括约肌松弛，腹泻时大便失禁。
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